منابع مشابه
Randomized Controlled Study of Intravenous Regional Anaesthesia for Forearm & Hand Surgery: Comparison of Lignocaine, Lignocaine with Ketamine & Lignocaine with Dexmedetomidine
Aims & Objectives: To evaluate the effect of Dexmedetomidine & Ketamine as an adjuvant to Lignocaine hydrochloride 0.5% 40ml in IVRA and to assess quality of anaesthesia, postoperative analgesia and side effects for hand or forearm surgery. Material & Method: Ninety patients were randomly assigned to three groups to receive IVRA for hand and forearm surgery: 40 ml of 0.5% Lignocaine and either ...
متن کاملSynthesis, anticonvulsant and neurotoxicity evaluation of 5-carbomethoxybenzoxazole derivatives.
A series of 5-carbomethoxybenzoxazole derivatives (6a-t) were prepared by using methyl-p-hydroxybenzoate. The identity of the compounds was confirmed on the basis of their elemental analysis and spectral data. In anti-MES test compounds 6b, 6d, 6h, 6j, 6m, 6p, 6q and 6s showed potent activity parallel to lipophilicity. Compounds 6b, 6d, 6k, 6n and 6s successfully passed the rotorod test without...
متن کاملA Case of Neurotoxicity Following 5-Fluorouracil-based Chemotherapy
5-Fluorouracil (5-FU) is a commonly used chemotherapeutic agent. However, its neurotoxicity is rare and not well recognized. We report a case of 5-FU neurotoxicity with organic brain syndrome and progression to multifocal leukoencephalopathy in a 44-year-old male patient having malignant gastrointestinal stromal tumor. 5-FU-induced neurotoxicity should, therefore, be considered as an important ...
متن کاملInfluence of premedication on lignocaine-induced acute toxicity and plasma concentrations of lignocaine.
The effects were studied, in eight healthy volunteers, of premedication with diazepam 0.14 mg kg-1 by mouth or hyoscine 6 micrograms kg-1 + morphine 0.2 mg kg-1 i.m., or no premedication, on toxic symptoms and plasma concentrations after rapid i.v. injection of lignocaine 1 mg kg-1. The alpha 1-acid glycoprotein (AAG) and albumin plasma protein fractions were assessed. A variety of mild central...
متن کاملA comparison of epidural anaesthesia with lignocaine, bupivacaine and a lignocaine-bupivacaine mixture in cats.
A mixture of 2% lignocaine (LIG) and 0.5% bupivacaine (BUP), at respective dose rates of 2 mg/kg and 0.5 mg/kg (LIG-BUP), was compared to LIG (4 mg/kg) and BUP (1 mg/kg) for lumbosacral epidural anaesthesia in 5 sedated cats. Each cat received all 3 treatment regimens at 1-week intervals. The cats were premedicated with an intramuscular injection of atropine sulphate (0.04 mg/kg) and ketamine h...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1995
ISSN: 0007-0912
DOI: 10.1093/bja/75.3.376